Author: Richard Broadhead

Seen any good films recently?

As the QuickFISH™ system continues to build a formidable reputation as the method of choice for the rapid identification of pathogens from blood cultures, the versatile PNA-FISH® technology on which it is based continues to demonstrate its flexibility and utility. Although PNA-FISH has been superseded by QuickFISH for diagnostic use with blood cultures, it is still ideally suited to a number of research applications in the field of medical microbiology, particularly three dimensional visualisation of microorganisms in biofilms.

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QuickFISH beats MALDI-TOF in the Clinical Microbiology Laboratory

In recent years, MALDI-TOF has become an increasingly popular means of pathogen identification in the clinical microbiology laboratory. Although this technique has proven to be robust and reliable in many cases, there are occasions where MALDI-TOF may not provide a clear species identification. Situations that MALDI-TOF can find challenging include:   Thankfully, the QuickFISH™ system

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The Clinical Benefits of Rapid Sepsis Diagnostics

Hospital Associated Infections (HAI) are a major concern for patient well-being and healthcare finances. Time is of the essence in treating such infections, generating increased pressure on laboratory professionals to provide prompt pathogen identification from blood cultures. Once species diagnosis is obtained, clinicians can then initiate more effective targeted antimicrobial therapy, minimising the use of

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Is Your MALDI-TOF Data Ambiguous?

QuickFISH™ Rapid Pathogen ID can help! The ideal complement to MALDI-TOF Although the MALDI-TOF system is becoming established as a technique of choice for routine use in the medical laboratory, nevertheless there are occasions where it may not provide a clear species identification. In these circumstances, the MALDI-TOF data may need to be verified using

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Enterococcus ID? Enter the Solution!

HPA statistics suggest that Enterococcus species are the fourth most reported cause of bacteraemias1, with the vast majority of cases caused by E.faecalis or E.faecium. Since the antibiotic sensitivity profiles of these two species differ significantly, identification of the specific species responsible for a particular infection is highly important in ensuring the most effective treatment.

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Accentuate the Positives, Eliminate the Gram Negatives

According to the Health Protection Agency1, bacteraemias caused by gram negative rods are now the most common type seen in NHS hospitals. Gram negative rods (GNR) include commonly encountered bacteria such as Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa. Bloodstream infections caused by such bacteria are associated with high mortality rates. However, as these species

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Counting the Cost of Septicaemia

Septicaemia is a serious, systemic illness that over the past 30 years has become increasingly common among hospitalised patients. Caused by bacteria and bacterial toxins circulating in the bloodstream, it is the 6th most common reason for hospitalisation (USA) and is responsible for more than 266,000 deaths every year1. Septicaemia can be very difficult to

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About Sepsis Diagnostics

Sepsis is a potentially life-threatening condition caused by the presence of micro-organisms such as bacteria (bacteraemia) and fungi (fungaemia) in the bloodstream. Disease progression can be rapid so effective clinical intervention in these cases requires prompt diagnosis and identification of the responsible pathogen.

The QuickFISH system offers unprecedentedly fast (20 minute) species identification of pathogens directly from positive blood cultures, allowing the reporting of pathogen identification at the same time as the reporting of Gram stain results. Implementation of QuickFISH for sepsis diagnostics can deliver

  • Improved patient outcomes
  • Decreased financial outlay
  • Optimised antibiotic use
  • Decreased patient length of stay