Gram-Negative QuickFISH for Diagnosis of Bacteraemia caused by Gram Negative Rods

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Bacteraemias caused by gram negative rods are now the most common type seen in NHS hospitals, and their incidence is increasing. The major proportion of these infections is accounted for by Escherichia coli bacteraemias. However Klebsiella pneumoniae and Pseudomonas aeruginosa are becoming increasingly significant also.

Gram negative rods look identical under the light microscope after gram staining and further identification to species by culture methods can take 24-48 hours. Compared to enterobacteria such as E.coli, P. aeruginosa is relatively resistant to many antibiotics, so positive species identification is needed to make an informed treatment decision.

E. coli
E. coli
K. pneumoniae
K. pneumoniae
P. aeruginosa
P. aeruginosa

Gram-Negative QuickFISH allows clinicians to rapidly ensure early, appropriate therapy for patients with Pseudomonas bacteraemia, while minimising the unnecessary use of aggressive and broad spectrum antibiotics.

Performance Data

Please see Instructions for Use (IFU) for complete performance data.

Conventional Identification

EC PA KP Other Species Total
QuickFISH EC 911,3 0 0 0 91
PA 0 522 0 1 53
KP 1 0 603 0 61
Negative 2 1 0 99 102
Total 94 53 60 100 307

 

1 Includes 9 blood cultures spiked with clinical strains of E. coli.
2 Includes 34 blood cultures spiked with clinical strains of P. aeruginosa.
3 Includes 1 mixed culture of E. coli and K. pneumoniae.

Key Benefits at a Glance

  • Identification of Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa directly from blood cultures in 20 minutes
  • Report Species identification at the same time as the gram stain result
  • Rapidly ensure early, appropriate therapy for patients with P.aeruginosa infections
  • Minimise the unnecessary use of aggressive anti-Pseudomonas therapies and broad-spectrum antibiotics

 

Download Gram-Negative QuickFISH Instructions for Use (IFU) Enquire about Gram Negative QuickFISH